We were eager to partner with Peggy Tighe, of Powers Law Firm, to walk you through a high-level overview of the 340B program. We discuss the structure, the original intent, the patients the program was established to serve, and the regulatory requirements for a successful 340B program. Under threat and opposition from various political and business interests from its very inception, we discuss current challenges and threats facing the 340B program and the Covered Entities who benefit from the associated savings.