RXinsider’s Pharmacy500 Academy now offers training on pharmacy courier services and pharmacy delivery, along with product comparisons and company breakdowns. Visit the Pharmacy500 Academy to learn more about last mile services.
Certain medications require to be shipped to patients at a consistently cold temperature or frozen in some cases.
Cold chain management aims at controlling the temperature and environmental conditions of medications through the entire supply chain, from manufacturing and storage, to transportation and distribution. Most pharmaceuticals are temperature sensitive, and when exposed to unsuitable environments, their potency may be impacted. The pharmaceutical cold chain starts at manufacturing facilities, where they research, formulate, package, and properly store products before mass distribution. The second phase involves distribution, where wholesalers are responsible for adhering to temperature guidelines by monitoring the environmental conditions of the warehouse and transportation. The third phase involves the pharmacy, usually a specialty pharmacy, shipping the medication to a patient’s home.
Rees Scientific specializes in protecting your valuable assets. Since 1982, Rees Scientific has been the industry standard for automated temperature monitoring. We offer continuous monitoring, centralized data collection, and simplified reporting. Monitor critical parameters such as temperature, humidity, differential Pressure, light control, etc. in vital equipment such as stability chambers, LN2 tanks, refrigerators, freezers, ultra-low freezers, incubators, etc. A single system can monitor a diverse facility with multiple locations while providing instant data access and sophisticated analysis right from your desktop computer, tablet or smartphone. Alarm notifications can be sent through telephone, text messages as well as e-mail.
View sensor conditions of your unit right from the Rees Scientific LCD display module. Ideal for pharmacies that house vaccines in their refrigerators. Monitoring temperature of vaccines is a crucial task that is regulated by many different government health organizations. The Rees Scientific LCD module complies with the guidelines of vaccines storage and handling from CDC, NIH, NIST, AAP, and PHAC.
ReesCloud is an optimal asset that provides a secure, fast and easy way to continuously monitor your critical equipment and environment conditions. Features include:
Today, we continue to lead the field, taking cues from our clients and their environmental challenges. We ensure that your critical equipment and devices are monitored and maintained to set a standard every day without exception and without fail. Rees Scientific will continue to build products and services that help provide resolutions for our customers. Our goal is to be a quality provider of systems, services and solutions for our clients.
Medical-grade Cold Storage you can trust!
Our TrueBlue™ commitment to quality, reliability, service, and support sets us apart. Since 1977, Helmer Scientific has led the industry by focusing on medical grade refrigerated products; designing and manufacturing innovative, specialized medical, pharmacy, and laboratory products that support our customers’ efforts.
Helmer Scientific medical-grade products maintain superior temperature uniformity and consistency throughout the entire storage chamber which is critical for ensuring that drugs and vaccines are stored within the proper temperature range and that all storage space can be fully utilized. Integrated access control provides an additional level of security by limiting and tracking user access. Our full line of undercounter and upright refrigerators and freezers, as well as pass-thru refrigerators and ultra-low freezers, include advanced alarm monitoring features, medication dispensing compatibility, and high-performance options and accessories for custom storage configurability.
GX Solutions Professional Medical-grade Refrigerators
Proper cold storage of medications and vaccines is critical in the healthcare environment, and often can be the difference between viable, effective products and ineffective or wasted product. With GX Solutions, professional, medical-grade cold storage is now available and takes cold storage to new levels. Focusing on temperature, noise and energy management, GX Solutions are the first cold storage solutions to optimize all three areas and offer a professional, medical-grade solution.
GX Solutions pharmacy and vaccine refrigerators are powered by OptiCool™ technology which pairs variable capacity compressor (VCC) technology and natural hydrocarbons (HC) to achieve performance characteristics that offer a superior storage environment. Optimized temperature management (uniformity, recovery and stability) provides confidence that contents are stored at the right temperature regardless of their location within the unit with fewer temperature deviations. In addition, noise levels are lowered, energy usage is reduced, and environmental sustainability initiatives are supported.
GX Undercounter Pharmacy Refrigerators
GX Upright Pharmacy Refrigerators
Pass-thru Refrigerators
Pass-thru refrigerators create a boundary between clean rooms and regular facility environments while permitting products to be removed from outside the clean room on a “first-in-first-out” basis, improving inventory control and boosting productivity.
BD Pyxis™ ES Refrigerator with Helmer Access Technology
The BD Pyxis™ ES Refrigerator provides integrated and secure, single-line access to high-risk and high-value refrigerated medications.
This industry-first product features precise temperature management and secure locking bins accessed only via the BD Pyxis™ Medstation™ ES. This enhances care by supporting medication safety, clinical workflow efficiency and regulatory compliance, while helping to reduce waste and mitigate the risk of diversion of refrigerated medications.
Laboratory Freezers
Laboratory freezers are designed specifically for the high demands of healthcare. Built-in monitoring systems provide continuous monitoring, real-time alarm notification, and status notification for worry-free storage, allowing your staff to focus on the critical functions of their job.
Undercounter
Upright
Ultra-Low Freezers
How It’s Made Matters. Reliable storage at -80°C. Our Ultra-Low temperature freezers are designed and developed to create a refined system that works together, providing optimized performance for the long-term storage of samples and medications.

Health Care Logistics offers a variety of refrigerators and freezers to meet your temperature-sensitive medication storage needs. From compact countertop units to full-size appliances, we make it easy to manage any critical drug storage situation. Multiple locking options are available so you can choose the level of security and accessibility to match your facility’s needs.
Enjoy these benefits, which are standard on our pharmacy-grade refrigerators:
Digital Microprocessor Temperature Controller: Pharmacy-grade refrigerators maintain precise settings of temperature cycles to meet today’s standards and display interior ambient temperatures in
F° or C°.
Forced Draft Circulation: Pharmacy-grade refrigerators provide required temperature uniformity and recovery after door openings.
Temperature Alarms: Pharmacy-grade refrigerators are equipped with audible and visual high and low temperature alarms so you can respond quickly and before expensive drugs are compromised.
Port Hole: Pharmacy-grade refrigerators feature an access port for CDC-compliant temperature monitoring system probes that allow you to track the status of your meds for better accuracy.
Keyed Door Lock: Pharmacy-grade refrigerators feature locks to provide additional security for high-value vaccines.
Check out our full inventory of medical-grade refrigerators, freezers and temperature monitoring accessories and find the perfect match for your medication storage needs!

Callan JMB is at the cutting edge of the cold chain specialty packaging market with sustainable, reusable thermal shippers backed by a dedicated tracking database and a patented sanitization process. We are uniquely positioned to support the pharmaceutical industry, where safety, quality, and reliability are critical. You can rely on our technology to maintain the integrity of your high-value vaccines, therapeutics, and diagnostics from distributor to pharmacy and even direct to patient. Our shippers use vacuum-insulated panels and phase-change materials validated to the highest standards for the best thermal protection for your compliance needs. Our systems allow high-velocity product fulfillment while our lease program reduces your storage, labor, and upfront costs with just-in-time delivery of shippers customized to your needs. Every shipper returns to us for SHIP2Q sanitizing and recertification, eliminating carbon emissions from the manufacture of replacements, unlike single-use shippers. A Callan JMB shipper is built to meet or exceed your acceptance criteria not only on the first shipment, but over and over until it is time for a zero-waste repurposing of all its well-traveled components. Whether cross-country or globally, our reusable specialty packaging ensures zero waste, zero risk of cross-contamination, and zero compromise on product quality and performance.
Closed Loop System
Whether you use your own reusable shippers or lease ours, we operate a closed loop system, reducing waste across all stages of shipping.
How It Works:
Benefits of the Closed Loop:
Inventory Management
We developed our own inventory management system with pharmaceutical logistics and compliance reporting as the highest priorities. Every customer accesses a customized, secure dashboard that shows the real time tracking status of every shipment, inventory quantities of items we store for you, and your current orders, and allows you to export the data at any time for your compliance reporting. The data is stored on our own secure servers and there is no limit on your access to historical data.
Benefits of our Inventory Management Services:
Fulfillment Services
We have 20+ years of experience in vaccine and pharmaceutical fulfillment and have developed efficient and cost-saving fulfillment lines in fully compliant facilities with highly trained personnel. We currently have fulfillment bases in Texas, Oregon and Illinois, wholesale distributors licenses in most states, and the ability to store product from -40C to +70C. We have safely shipped millions of doses of vaccines and therapeutics for the States of Texas and Oregon and for the City of Chicago, as well as for commercial clients across the US. We specialize in pinpoint delivery of small payloads in the US and are capable of managing bulk shipments globally.
Benefits of our Fulfillment Services:
For more details and to ask questions about our services email us at solutions@coldchain-tech.com, or visit our website at callanjmb.com.

Since 2013, DiNovo Cleanroom Supplies & Packaging Solutions has been a leader in delivering cleanroom consumables, disinfectants, medical devices, cold chain shipping essentials and tailored packaging solutions to the compounding and specialty pharmacy marketplace.
Our foundation is built on trust, innovation, and compliance. As a dual-source supplier and educational resource, DiNovo partners with top global manufacturers to help pharmacies:
We serve as a strategic partner to pharmacies navigating an increasingly complex regulatory landscape — helping them streamline operations while improving patient outcomes.
We provide a broad array of pharmacy packaging products, including:
Whether you’re a high-volume pharmacy or a niche compounder, our low minimum order quantities (MOQs) and quick turnaround times make it easy to build a consistent, branded experience for your patients.
For pharmacies managing temperature-sensitive medications or home delivery, DiNovo provides:
These products are designed to ensure compliance with USP <1079> and protect product viability during transit. ISTA Certified shipping solutions are available!
As part of our cleanroom and compliance support offerings, we also deliver:
These help pharmacies maintain cleanroom classifications, meet audit requirements, and mitigate risk.
We supply USP <797> and <800> compliant cleanroom products to support sterile and non-sterile compounding operations:
Our team is well-versed in cleanroom certification requirements and can assist in selecting products that meet your operational standards.
As a one-stop-shop for your pharmacy, we offer a variety of medical devices and products needed in the compounding process:
To deliver innovative, compliant, and reliable pharmacy supply solutions that support operational excellence and protect patient safety.
To be the pharmacy industry’s most trusted partner for cleanroom products, custom packaging, and cold chain logistics, continuously driving forward the standards of pharmacy care.
DiNovo supports customers across the entire spectrum of pharmacy practice, including:
Our consultative approach ensures pharmacies of all sizes receive tailored solutions based on volume, regulatory needs, and branding goals.
Whether you’re scaling operations, rebranding your packaging, or building a new cleanroom — DiNovo is your partner in every phase of pharmacy growth.
Founded in 1948, Follett is a leading manufacturer of innovative equipment for the healthcare market.
Follett high-performance, medical-grade refrigerators and freezers deliver exceptional reliability and consistent temperatures for critical product storage. A full line of stainless steel countertop, undercounter and upright refrigerators and freezers provide healthcare’s most consistent temperature performance and a full set of user-valued alarming, monitoring and storage features. Compatible with all medication dispensing and temperature monitoring systems, all Follett refrigerators and freezers come with options and accessories for customization to meet a facility’s needs.
Countertop Medical Grade Refrigerators and Freezers
Ideal for small storage needs, Follett forced-air countertop refrigerators and freezers offer superior temperature performance in space-saving configurations. 1 and 2 cubic foot models fit on standard 24” deep counters. External digital temperature display in user-selective F or C offers integral high/low alarming and display sleep mode.
Undercounter Refrigerators and Freezers
Follett Performance Plus undercounter refrigerators and freezers provide superior high-performance temperature control for critical product storage. Designed for use below standard and lower ADA-compatible counters, Follett Performance Plus delivers outstanding reliability and user-valued features that set us apart from the competition. Heavy-duty forced air cooling delivers consistent temperatures and quick recovery to maintain your valuable medications at the right temperature. Full stainless steel construction and heavy-duty components ensure long-term reliability.
Upright Refrigerators and Freezers
High-performance upright refrigerators and freezers designed specifically for healthcare. From back plenum air ducts that ensure consistent, cabinet-wide cooling, to a feature rich, intuitive alarming and display interface, Follett upright refrigerators and freezers take the worry out of critical product storage, allowing your staff to focus on the job at hand.
Digital Data Logger
The digital data logger complies with all CDC vaccine storage guidelines. Vaccines require storage within a defined temperature range in order to maintain their potency. The data logger with detachable probe records and stores temperature information at user-programmable intervals for continuous monitoring. It features a touchscreen display and includes dry contacts for remote alarming. The data logger can be installed on any Follett refrigerator or freezer.

American Biotech Supply, a Horizon Scientific, Inc. brand, provides a full range of temperature-controlled equipment to our customers across the healthcare, laboratory and clinical research, pharmaceutical, and industrial segments. The extensive portfolio of quality products ranges from small capacity countertop refrigerators and freezers, including special purpose, application-specific models, as well as cryogenic freezers for long-term sample preservation. Ensuring customer requirements are met, all products are designed in a variety of configurations, from general purpose cold storage to medical and pharmaceutical storage with stringent temperature performance requirements. With over 25 years of experience, American Biotech Supply excels at quickly developing customer solutions at competitive price points while providing industry-leading service levels. The American Biotech Supply advantage includes a comprehensive array of products and services to meet your temperature-controlled storage needs, an industry leading warranty, and many models are available from in-stock inventory and ready to ship.
Your One Stop Shop for Cold Storage Solutions including:
Our Portfolio of Medical Grade Cold Storage Equipment includes:
ABS Cold Storage Product Line Highlights:

Corepoint™ Scientific, a Horizon Scientific, Inc. brand, provides a full range of temperature-controlled equipment to our customers across the healthcare, laboratory and clinical research, pharmaceutical, and industrial segments. The extensive portfolio of quality products ranges from small capacity countertop refrigerators and freezers, including special purpose, application-specific models, as well as specialty upright models including Blood Bank Refrigerators and Plasma Freezers. Ensuring customer requirements are met, all products are designed in a variety of configurations, from general purpose cold storage to medical and pharmaceutical storage with stringent temperature performance requirements. The Corepoint™ Scientific advantage includes a comprehensive array of products and services to meet your temperature-controlled storage needs, an industry leading warranty, and many models are available from in-stock inventory and ready to ship.
• Dedicated Production Lines
• Experienced Customer Service Support
• Knowledgeable Technical Service and Support
• Logistics Solutions
• Sustainability – offering largest number of cooling options with Natural Refrigerants
• Sizes range from 1 cu. ft. – 72 cu. ft. capacity
• Undercounters & Countertops – with Built in & Freestanding options
• High Performance Uprights
• Blood Bank Refrigerators
• Sizes range from 1 cu. ft. – 72 cu. ft. capacity
• Undercounters & Countertops – with Built in & Freestanding options
• High Performance Uprights
• Plasma Freezers
• Low Temperature options (-30°C, -40°C, & -86°C Ultra Low)
• Utilizes a stacked design for maximizing space
• Humidity Stability Test Chambers
• Temperature Test Chambers
• Ideal for stability testing, shelf life, package testing and accelerated aging for a variety of products and packaging
• Controlled Room Temperature Cabinets – temperature assurance for ambient medication storage
• Controlled Auto Defrost Freezers – patented technology provides convenient frost removal while maintaining “spike-free” temperature ranges
• Full range of sizes, 1 cu. ft. – 72 cu. ft., to meet all capacity needs
• Precise temperature control for storage of critical vaccines and samples
• Data-logging and temperature monitoring solutions available
• Most models utilize environmentally friendly, natural Hydrocarbon refrigerants
• Low global warming potential and zero ozone depletion
• Energy efficient design lowers operating costs
• ADA compliant and Energy Star Certified models available
• Audible and visual alarms with remote alarm capability
• Many models in stock and ready to ship
The Pharmacy500 is awarded to 500 pharmacy supply chain businesses and associations that significantly impacted dispensing pharmacies in the U.S. over the past year.
The following are complimentary benefits extended to Pharmacy500 companies and associations (coming this spring!)

Company Background & History
Coldkeepers is a pioneer and leader in providing innovative thermal shipping solutions tailored to address the most demanding cold-chain challenges. Our proprietary shipping products, combined with our adaptable, logistics-based service, maintain and preserve the cold-chain process for the unique needs of clients in the pharmaceutical, health, and life science industries.
Co-founded in 1998 by Lang Flowers, III (CEO) and Lionel de Bazelaire (COO), and headquartered in picturesque Thomasville, Georgia, Coldkeepers remains equally committed to environmentally responsible packaging design, domestic production, and continuing innovation.
Product Overview
Coldkeepers’ patented shipping supplies provide state-of-the-art protection for your temperature-sensitive products from warehouse to doorstep. Ranging from curbside recyclable one-piece insulated box liners to thermally insulated mailers, pouches, and gel packs, our product line is designed to address the industry’s toughest cold-chain standards.
Coldkeepers products come with leading cold supply chain expertise and experience. Our trained specialists will work closely with your team to develop a tailored thermal packaging solution so your products can reach their destination safely.
Features & Options
Introducing the Penguin Mailer: Superior Cold-Chain Protection
At Coldkeepers, we’re proud to present our cutting-edge solution to cold-chain shipping — the Penguin Mailer. Engineered with superior craftsmanship and robust materials, the Penguin Mailer offers unparalleled protection for products in transit, setting a new industry standard. The Penguin Mailer ships flat at 15% of its normal size. This efficient packaging solution dramatically reduces storage space requirements and freight costs, making it ideal for small specialty pharmacy locations. Available in sizes: 9″x12″, 12″x16″, 15″x20″, and all with 1.375″ foam. The Penguin Mailer covers 95% of pharmacy shipments.
Curbside Recyclable One-Piece Insulated Liner
Our newest liners are suitable for shipments of controlled room temperature, refrigerated, or frozen pharmaceuticals between 2-8°C for 24 to 48+ hours (use with gel packs or dry ice to extend transit times). They boast a flexible design that allows them to ship flat and save on inbound freight and warehousing expense. Manufactured from postindustrial paper products, our liners are not only certified curbside recyclable by Western Michigan University but also third-party ISTA lab tested and certified by world renown WuXi AppTec testing lab.
One-Piece Extreme Liner
Third-party tested and certified by WuXi AppTec, these liners will keep your temperature-sensitive products at the right temperature for one to two day shipments. Our team of dedicated specialists can also help you design a custom pack-out to ensure your products arrive without breaking the cold chain. Our one-piece extreme liners can be used in conjunction with gel packs or dry ice for products that must be kept at a preset temperature for extended periods of time.
Extreme Thermal Mailers
Our Extreme Mailers are great for small parcels of temperature-sensitive medications when you need to ensure your prescription drug shipments stay at the right temperature during transit. Designed to fit inside UPS and FedEx Express boxes, the Extreme Insulated Mailers feature an open cell foam inner liner providing your products with unsurpassed levels of thermal and shock absorbing protection.
Insulated Pouches
Our line of Insulated Pouches features an easy-to-use double track pressure closure to ensure a tight and leakproof seal. They keep items cold for several hours or longer when paired with a frozen gel pack, ice or dry ice. Our exclusive line of durable pouches with built-in gel packs makes achieving those longer cooling times easy and encourages reuse. Simply freeze the pouch to charge the built-in gel pack, then you (or your customer) can reuse it over and over.
Experience the Coldkeepers Difference
More Information
To request a sample or connect with our experts, please visit our website www.coldkeepers.com or contact us at
RXinsider’s Pharmacy500 Academy now offers training on pharmacy courier services and pharmacy delivery, along with product comparisons and company breakdowns. Visit the Pharmacy500 Academy to learn more about last mile services.
Enhance your understanding of pharmacy delivery and shipping with RXinsider’s Pharmacy500 Academy, which offers in-depth training on cold chain logistics and cold chain supplies. Discover detailed company breakdowns and product comparisons designed to support your cold chain operations.
This visual represents the comprehensive structure of the modern pharmacy landscape, capturing the interconnected roles, settings, specializations, and operational elements that support patient care and drug distribution. Developed by RXinsider, the ecosystem map is designed to serve as a foundational reference for education, training, communication, and strategic planning across the pharmacy industry.
Discover the stories, research, and reports from real pharmacies, health systems, hospitals, and infusion centers.
RXinsider’s Pharmacy500 Stock ETF is a stock portfolio comprised of the largest publicly traded companies in the Pharmacy500.
This report offers a concise snapshot of the Pharmacy500 companies by highlighting new company additions, and examining regional distributions, practice settings, supply chain categories, and the key conferences attended.
B Medical Systems
Cardinal Health
Care Services, LLC
CaryHealth
Cold Chain Technologies
Coldkeepers
Datarithm
Datascan Pharmacy, Inc.
MAXQ
Mideast Delivery Solutions
Nimble
Nordic Cold Chain Solutions
Optum, Inc.
ParcelShield
Phox Health, Inc.
RedSail Technologies, LLC
Rx2Go