Pharmacy500 Marketplace

Closed System Drug-Transfer Devices (CSTDs)

CSTD Manufacturers and Efficacy, Closed System Transfer Device Comparisons and Studies, CSTD and USP 800 Regulations, Leur-Lock Compatibility and Assembly, Chemotherapy / Hazardous Drugs, NIOSH...

Aisle OVERVIEW

Pharmacy Closed System Drug-Transfer Devices (CSTDs) are specialized mechanical devices designed to prevent the escape of hazardous drug vapors, aerosols, and liquids during drug preparation, transfer, and administration. They are used in pharmacy and healthcare settings to ensure the safe handling of hazardous drugs, protecting healthcare workers, patients, and the environment from exposure. CSTDs are a critical component of safety protocols in pharmacy practice, ensuring a safer working environment and minimizing risks associated with the handling of hazardous drugs.

Company Profiles

Pharmacy500

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The Pharmacy500 is awarded to 500 pharmacy supply chain businesses and associations that significantly impacted dispensing pharmacies in the U.S. over the past year.

Pharmacy500 Benefits

The following are complimentary benefits extended to Pharmacy500 companies and associations (coming this spring!)

  1. Company listings in the Platinum Pages Buyer’s Guide, 20Ways publications, and RXinsider website
  2. Company inclusion in the 20Ways themed Buyer’s Guide
  3. Unlimited job postings in the Pharmacy500 Career Center *Unlimited through 2025
  4. Tradeshow promotional resources including Pharmacy500 floor stickers and lanyards
  5. Two posts (annually) in RXinsider’s Pharmacy Market BUZZ news feed

Who are the Pharmacy500 and what are the selection criteria?

The Pharmacy500 includes:

  1. Companies within the Pharmacy Supply Chain
  2. National Pharmacy Trade Associations

The Pharmacy500 Selection Committee applies the following criteria to determine the list of 500:

  • Offers and actively markets at least one product or service to dispensing pharmacies
  • Dispensing pharmacies comprise at least 25% of their customer base
  • Has an estimated annual revenue exceeding $500,000
  • Has five or more full-time employees, and has been in business for more than two years
  • Has a national presence
  • Exhibited at one of the following national conferences in the previous year: APhA; ASCP Annual Meeting & Exhibition; Asembia’s Summit; ASHP Midyear Clinical Meetings & Exhibition; Cardinal Health RBC; McKesson ideaShare; NACDS Total Store Expo; NASP Annual Meeting & Expo; NCPA Annual Convention and Expo; Pharmacy Futures (ASHP Summer); ThoughtSpot.

The following supply chain segments are critical to pharmacy operations and patient care, but are excluded from the Pharmacy500 simply due to volume:

  • Manufacturers and Merchandisers of Pharmaceuticals
  • Manufacturers and Merchandisers of Devices and OTC Products
  • Colleges of Pharmacy
  • State Associations
  • Government Agencies and State Boards of Pharmacy
  • Pharmacy Fraternities & Sororities
  • Dispensing Pharmacies, Health Systems, Chains, Payors, and PBMs

Product Highlight SHOWCASE

Subject Matter Expert & Thought Leader PROFILES

Resources & Awareness

The Pharmacy500 are the pharmacy operations supply chain businesses and associations that significantly impacted dispensing pharmacies over the past year. This report analyzes the Pharmacy500 logos and their visual elements to provide insight into branding trends.

Learn more about compounding insights and Pharmacy500 companies behind the industry in our Pharmacy500 Platinum Pages 2026 publication!

The 2026 Pharmacy500 Companies Market Teardown report provides a concise snapshot of the 2026 companies, highlighting new additions, examining regional distributions, practice settings, supply chain categories, and key conferences attended.

RXinsider’s Pharmacy500 Careers Outlook report identifies key employment trends and workforce dynamics across Pharmacy500 companies. Check out this report to learn more about open position trends and the current state of the job market impacting the pharmacy supply chain!

Fortune Magazine’s annual Fortune 500 ranks the largest U.S. companies by revenue. Many leaders in healthcare and pharmaceuticals drive medication production, distribution, and patient access. This report highlights their impact on the pharmacy industry.

STAQ Pharma supports hospitals with their CSTD portfolio and IV solutions, strengthening hazardous drug preparation through the Methotrexate CSTD Kit, which pairs ready-to-administer methotrexate with ICU Medical closed-system components. To learn more, visit their profile in the 20Ways Winter Hospital publication.

In this case study we look at how Summa Health partnered with Leiters Health to implement a compounded, opioid-free nerve block formulation in their operating rooms, significantly reducing opioid use, extending shelf life of the preparation, and easing the pharmacy’s compounding burden.

Pharmacy Closed System Drug-Transfer Devices (CSTDs) are specialized mechanical devices designed to prevent the escape of hazardous drug vapors, aerosols, and liquids during drug preparation, transfer, and administration. The Closed System Drug-Transfer Devices Report provides insight into the Pharmacy500 companies that produce CSTDs, including product comparisons, other company insights, and more.

RXinsider’s Pharmacy500 Academy now offers training on closed system drug-transfer devices (CSTDs), with product comparisons and company breakdowns featuring companies like EQUASHIELD, ICU Medical, and BD. Visit the Pharmacy500 Academy to learn more about closed system transfer devices.

Pharmacy500

COMPOUNDING 

Accu-Chart Plus Health Care Systems
Acute Care Pharmaceuticals (Hospeco Brands Group)
AirCare Automation
AirClean Systems
AIS Healthcare
Alliance for Pharmacy Compounding (APC) Allied Pharmacy Products
Allometrics
American College of Apothecaries (ACA)
ARL Bio Pharma
ARxIUM
Associates of Cape Cod, Inc
B. Braun Medical Inc.
Baxter
Berkshire Corporation
Blue Thunder Technologies
Bureau Veritas
Cardinal Health
Central Admixture Pharmacy Services, Inc. (CAPS)
ChemoGLO
CINTAS Corporation
Cleanetics
Cleanroom Connection
ConsortiEX Inc.
Contec, Inc.
Cordica Medical
CORMED
CPS Solutions, LLC
CurifyLabs
DiNovo Cleanroom Supplies and Packaging Solutions
Eagle Analytical Services
EMSL Analytical, Inc.
EQUASHIELD
Esco
Eurofins Analytics
Fagron
FLAVORx
Grifols
Hardy Diagnostics
Health Care Logistics, Inc.
Helmer Scientific
ICU Medical
Innovatix, LLC
Integrated Medical Systems, Inc. (IMS)
International Journal of Pharmaceutical Compounding (IJPC)
International Medical Industries Interphex
ISO-MED, Inc. (Hospeco Brands Group)
IsoTech Pharma
Lakeland Industries, Inc.
LGM Pharma
LifeFile
Medi-Dose, Inc./EPS, Inc.
Medical Technology Associates, LLC
Medisca Inc.
MediZap
MedSafety Solutions
MedXL Inc.
Modular Cleanrooms, Inc.
Modular Devices
MPS Pharma & Medical, Inc.
NuAire, Inc.
Nuvai Medical Technologies
P&C Pharma
PAAS National LLC
Parasol Medical, LLC
Particle Measuring Systems, Inc.
PCCA
Pestle (Accreditation Partners LLC)
Pharma Source Direct
Pharmacy Stars, LLC
Prudential Cleanroom Services
Pure Microbiology, LLC
Q.I. Medical Inc
QleanAir Scandinavia
Quality Solutions
QUESS 360 – Pharmacy Solutions
Rees Scientific
Samson Medical Technologies, LLC
Sharps Medical Waste Services
Shepard Medical Products | CareMates
SpecializedRx Products, LLC
Spectrum Pharmacy Products
Technical Safety Services
The Baker Company
TICKERWORKS
Total Pharmacy Supply, Inc.
Travis CleanAir, Inc.
TRC Healthcare
U.S. Micro-Solutions, Inc.
Vileda Professional
Visante LLC
Willow Birch Pharma, Inc.
Winfield Laboratories, Inc.
WM-PharmEcology
Wolters Kluwer
WorkingBuildings
Yukon Medical, LLC

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