Learn more about Point – of – Sale (POS) Systems insights and Pharmacy500 companies behind the industry in our Pharmacy500 20Ways publication!
A POS (Point of Sale System) is a technology platform used by pharmacies to process sales transactions, manage inventory, and streamline various operational tasks. This system typically integrates hardware (e.g., cash registers, barcode scanners, receipt printers) and software to enable pharmacies to efficiently conduct business transactions, manage customer data, and ensure compliance with regulatory requirements.
POS systems integrate various functions, such as prescription handling, payment processing, inventory control, and insurance claims, to enhance efficiency, improve accuracy, and ensure compliance with regulations. By providing real-time data and valuable insights, a POS system plays a crucial role in supporting the operational success of a pharmacy.
The Pharmacy500 is awarded to 500 pharmacy supply chain businesses and associations that significantly impacted dispensing pharmacies in the U.S. over the past year.
The following are complimentary benefits extended to Pharmacy500 companies and associations (coming this spring!)
Have you outgrown your pharmacy system?
That’s what many community pharmacies are asking themselves as they experience “growing pains”. While your pharmacy staff fights insurance claims, error messages, uncooperative doctor’s offices, and a computer system that seems slower than it used to, your customers still expect the same fast service they have always received from you. Many pharmacies are realizing that their computer system cannot keep up with their growing business. What is the answer to their problems? Many pharmacies have found a solution with the RXQ™ Pharmacy Management Software.
RXQ Features:
Here at Liberty, we believe that RXQ is a next-generation pharmacy management system. It’s not just about technology, although RXQ is built on Microsoft’s new technology platform. It’s not just the feature list. More than anything, we believe that it is the user experience. Prescriptions can be filled quickly and accurately. Pharmacists who switch to often tell us RXQ is the easiest system they have ever used.
“RXQ is the most user-friendly and easy-to-use system that I have worked on, and other pharmacists that use RXQ tell me the same”
James Kelley
Kelley Drug
“There is one word that separates Liberty Software from all others – SERVICE! I have come to know, respect and appreciate their entire staff. The pharmacy system and support is the best available. If you are wanting a system and service that is unmatched you will not find a better company”
Lindsey Walker, Owner
Walker Pharmacy
By harnessing the power of technology, PrimeRx empowers pharmacies to achieve operational excellence and superior patient care. With a legacy of innovation and a focus on customer satisfaction, PrimeRx is shaping a new era in pharmacy management solutions.
At the core of our technology is PrimeRx Enterprise, developed 30 years ago, which offers comprehensive, integrated functionality for all pharmacy types. This robust system is managed via traditional on-premises hardware and software, providing reliable and efficient operations for pharmacies.
Expanding its comprehensive pharmacy solutions portfolio, PrimeRx introduces PrimeRx CLOUD and PrimeRx MARKET. PrimeRx CLOUD offers pharmacists unparalleled flexibility, accessibility, and security, ensuring they can manage their operations from anywhere with peace of mind. PrimeRx MARKET, the leading pharmaceuticals e-commerce marketplace, provides safe and secure access to both ADD and non-ADD wholesalers. With real-time price competition, pharmacies can effortlessly find the best deals, enhancing their purchasing power and operational efficiency.
Together, PrimeRx Enterprise, PrimeRx CLOUD, and PrimeRx MARKET form the PrimeRx ecosystem, delivering cutting-edge solutions that drive success and elevate patient care. We invite you to learn more about our innovative solutions and discover how PrimeRx can help your pharmacy thrive.

Pharmacy Management System for closed-door, institutional, and long-term care pharmacies
Flexible Pharmacy Management
Integra’s PrimeCare is designed for closed-door, institutional, and long-term care pharmacies serving skilled nursing, mental health, and assisted-living facilities. Our Pharmacy at a Glance dashboard displays queue information to alert you to potential bottlenecks. PrimeCare is developed specifically for the rigors of institutional pharmacy and provides time-saving and productivity-enhancing technology, including workflow and simplified billing and reporting.
WebConnect™
With WebConnect, facilities can view profiles, order refill medications, maintain ancillary orders, access clinical information, and print MARs. WebConnect’s application for iPad® and other devices is intuitive and provides mobility within the facility in a secure, HIPAA-compliant environment.
Interfaces
PrimeCare interfaces with other technologies to improve efficiency, reduce duplicate data entry, and improve customer service. Our hundreds of ready-made interfaces, including most eMARs, document management, and packaging systems use industry standards, such as HL7®, XML, web services, and NCPDP® SCRIPT 10.6 to ensure reliable, accurate communications.
Built-in Forms
Fill Lists streamline unit dose filling and billing, and PrimeCare contains easy-to-use forms, including:
PrimeCare integrates with QS/1’s SystemOne® for HME, Web Refill Services, Remote Backup, Multi-Site Management (MSM™) and many other QS/1 products and services.
Contact us by clicking the links above!
Learn more about Point – of – Sale (POS) Systems insights and Pharmacy500 companies behind the industry in our Pharmacy500 20Ways publication!
Learn more about Point-Of-Sale insights and Pharmacy500 companies behind the industry in our 20Ways Spring Retail 2026 publication!
In some cases, pharmaceutical manufacturers have agreements with pharmacy switch
vendors that allow manufacturers to automatically apply savings programs during the claim process. To learn more about pharmacy eVouchers, check out our workflow graphics in the Pharmacy Switch Software & Services report!
What is a pharmacy switch? A pharmacy switch is essentially a “digital middleman” that helps route prescription payment information between pharmacies and payors. Gain insight into the pharmacy switch workflow by checking out our pharmacy switch workflow graphic!
Explore highlights from RXinsider’s Pharmacy Switch Software & Services report. Gain insights into the four Pharmacy500 companies that offer a pharmacy switch service, including a division breakdown, product highlights, and concept overviews, by visiting our Market Intelligence page.
The Pharmacy500 are the pharmacy operations supply chain businesses and associations that significantly impacted dispensing pharmacies over the past year. This report analyzes the Pharmacy500 logos and their visual elements to provide insight into branding trends.
Explore highlights from RXinsider’s Retail Point-of-Sale (POS) & Payment Services report. For additional insights into Pharmacy500 companies providing pharmacy checkout systems, including a look at the history of the pharmacy cash register, visit our Market Intelligence page.
The 2026 Pharmacy500 Companies Market Teardown report provides a concise snapshot of the 2026 companies, highlighting new additions, examining regional distributions, practice settings, supply chain categories, and key conferences attended.
RXinsider’s Pharmacy500 Careers Outlook report identifies key employment trends and workforce dynamics across Pharmacy500 companies. Check out this report to learn more about open position trends and the current state of the job market impacting the pharmacy supply chain!
RXinsider’s Market Threats report identifies key trends and market risks analyzed from publicly traded companies within the Pharmacy500. Check out this report to learn more about the challenges in the pharmacy operational supply chain!
Fortune Magazine’s annual Fortune 500 ranks the largest U.S. companies by revenue. Many leaders in healthcare and pharmaceuticals drive medication production, distribution, and patient access. This report highlights their impact on the pharmacy industry.
Learn more about Workflow insights and Pharmacy500 companies behind the industry in our Pharmacy500 Platinum Pages publications!
In this case study, we take a look at how Belmar Pharma Solutions streamlined payment processing with Wind River Payments, improving customer experience, PCI compliance, transaction security, and scalable pharmacy operations.
Paladin Point of Sale integrates with Rx systems to speed checkout and OTC inventory, capture compliance data, sync returns to pharmacy records, and supports barcode scanning. Learn more by exploring our 20Ways publications!
PharmacyOne cloud pharmacy management software streamlines workflows, improves profitability and compliance, secures data, and speeds staff onboarding with smooth transition support. Learn more by exploring our 20Ways publications!
This report provides a comprehensive breakdown of RedSail Technologies’ company structure, key products, company history, and integrations and collaborations. Check out this report to learn about RedSail Technologies.
In this case study, we take a look at how AHF Pharmacy utilized Epicor’s point-of-sale (POS) software to enhance its prescription delivery workflow.
In this case study, Cardinal Health partnered with Square to help independent pharmacies adopt modern payment options to streamline operations and improve customer service.
RXinsider’s Pharmacy500 Academy now offers training on pharmacy Point-of-Sale (POS) systems. The training includes product comparisons and company breakdowns that covers all pharmacy checkout software and registers. Visit the Pharmacy500 Academy to learn more.
Accu-Chart Plus Health Care Systems Asteres Inc.
Capsa Healthcare
CarePoint
Celerant Technology
Codonics
Cypress Software, Inc.
Digital Business Solutions, Inc. EnlivenHealth
Epicor Software Corporation
Euclid Medical Products
Everyware
Health Care Logistics, Inc.
iA
iLocalBox
InstyMeds
Jays Company
Keycentrix, LLC
Liberty Software
Lumistry
Magstar Inc.
McKesson Corporation
Medi-Dose, Inc./EPS, Inc.
Medical Packaging Inc., LLC (MPI)
Medtel Communications (Lumistry)
Nimble
Omnicell
Outcomes
Paladin Data Corporation
PAS Packaging (Pharmacy Automation Supplies) Phoenix Pharmatech
PK Telehealth (TCE Group)
PrimeRx
RedSail Technologies, LLC
Keycentrix, LLC
Liberty Software
Lumistry
Magstar Inc.
McKesson Corporation
Medi-Dose, Inc./EPS, Inc.
Medical Packaging Inc., LLC (MPI)
Medtel Communications (Lumistry)
Nimble
Omnicell
Outcomes
Paladin Data Corporation
PAS Packaging (Pharmacy Automation Supplies) Phoenix Pharmatech
PK Telehealth (TCE Group)
PrimeRx
RedSail Technologies, LLC
Retail Management Solutions, LLC RevSpring, Inc.
Rx Systems, Inc.
RxScan
ScriptPro LLC
Source Communications LLP Speed Script
Suncrest Solutions
Tabz (FKA HealNow)
Unidoses
UNIWEB, Inc.
VOXO
VytlOne
Wind River Payments
XiFin
Zebra Technologies Corp.