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Evaluation of LAL and Recombinant Endotoxin Alternative Assays for an Assessment of Endotoxin Detection Specificity

Evaluation of LAL and Recombinant Endotoxin Alternative Assays for an Assessment of Endotoxin Detection Specificity


The peer-reviewed data on recombinant BET is here, and it says that recombinant BET methods are inferior to LAL. The European Journal of Pharmaceutical Sciences published new research that challenged the recombinant alternatives to the LAL method, and the results from this study demonstrated that all recombinant products have a propensity to underpredict endotoxin activity when compared to gold standard, LAL. 


Still considering evaluating an alternative endotoxin testing method? View the peer-reviewed research article, Evaluation of Limulus Amebocyte Lysate and Recombinant Endotoxin Alternative Assays for an Assessment of Endotoxin Detection Specificity. 


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Charles River

Charles River News & Announcements

In today’s world, quality and compliance are non-negotiable, and yesterday’s standards are no longer sufficient to meet the demands of a constantly evolving landscape. The field of quality control microbiology is undergoing a disruptive revolution to safeguard patient safety, evolving beyond traditional methods to optimize resources, minimize human error, enable sustainable alternatives, and maintain consistent quality standards. Every test, every result, and every data point define the success of life-changing therapies. That’s why we’re leading a new paradigm, one that redefines efficiency, sustainability, and innovation. Let’s rethink the future of microbial quality control, where modern, automated, data-centric, and scalable solutions are the norm, empowering you to stay ahead in a dynamic regulatory and operational landscape.  Together, we are not just preparing for the future. We’re rethinking it. Because every moment matters.

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Posted by: RXinsider Staff

RXinsider is a multimedia publishing and technology company offering print publications, digital platforms, events, and content creation services to the B2B pharmacy market.

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