American Biotech Supply (ABS) offers a line of NSF/ANSI 456-certified refrigeration units—engineered and tested to meet the most rigorous criteria for vaccine storage. This certification, developed by NSF International in collaboration with the Joint Committee on Vaccine Storage, establishes specific construction and performance standards that go far beyond conventional pharmacy-grade refrigerators. The result is greater reliability, precision, and peace of mind for healthcare providers managing high-value, temperature-sensitive vaccines.
So what makes an NSF/ANSI 456-certified unit different? The answer lies in the testing. These units are evaluated using Vaccine Simulation Devices (VSDs)—aluminum thermal ballasts that mimic real vaccine vials under stress-tested conditions. During testing, VSDs are placed in extreme positions within the chamber to simulate 15 worst-case storage scenarios. The units must maintain strict temperature ranges (2°C to 8°C for refrigerators), recover quickly after 3-minute door openings, and demonstrate tight stability and uniformity across all probes. Beyond performance, these units feature forced-air circulation, premium temperature controllers, and plenum construction for even cooling—features that many standard pharmacy fridges lack.
Why NSF/ANSI 456 Certification Matters:
- Must maintain precise temperatures during and after door openings.
- Uses VSDs to replicate worst-case vaccine storage scenarios.
- Includes plenum air distribution for consistent internal temperatures.
- Ensures performance aligns with CDC’s vaccine storage guidelines.
- Tested and validated by accredited labs for quality assurance.
With NSF/ANSI 456 certification, these units offer verified performance that supports compliance, safeguards vaccine integrity, and aligns with the most stringent cold chain standards in the industry.



