SureCost helps pharmacies control spending and simplify purchasing by centralizing vendors, improving inventory visibility, and giving teams the tools to make smarter, more cost-effective decisions.
Drug Procurement Software for pharmacies is a specialized software solution designed to streamline and automate the process of sourcing, comparing, purchasing, and managing the acquisition of medications and pharmaceutical supplies. It enables pharmacies to maintain optimal stock levels, compare wholesalers, negotiate with suppliers, and ensure compliance with regulatory and financial requirements.

At AdvanceNet Health Solutions (ANSHealth), we’re dedicated to being the world’s premier ePharmacy technology company. Our ePostRx product enables pharmacies to facilitate higher fulfillment volumes, enhance patient care and increase profitably by supporting multiple business models, including Electronic Scripts, Retail, Chain Retail, Mail-Order and Central Fill. Now ePostRx is the healthcare industry’s first and only open source, enterprise pharmacy solution licensed under GNU General Public License (GPL). So if your business requires:
Then contact ANSHealth and get involved with the ePostRx community today!
Join Over 2,000 Pharmacists and Staff Who Trust C2 Keep to Bring Peace of Mind
C2 Keep is a cloud-based, fully integrated controlled substance reporting and compliance solution designed specifically for pharmacies. Founded by former pharmacy director Roland Achenjang after experiencing an embarrassing audit, C2 Keep was built to eliminate the same compliance challenges he and countless others have faced.
By automating manual tasks, delivering real-time insights, enhancing security, and simplifying reporting, C2 Keep empowers pharmacies to stay compliant and focus on what matters most: ensuring patients receive the right medication at the right time.
Why Pharmacies Choose C2 Keep
Ready to Simplify Compliance?
Whether you’re a small independent pharmacy or part of a larger chain, C2 Keep scales to meet your unique needs, providing a flexible compliance solution that grows with your business. Visit c2keep.com and schedule a demo to learn more!
The Pharmacy500 is awarded to 500 pharmacy supply chain businesses and associations that significantly impacted dispensing pharmacies in the U.S. over the past year.
The following are complimentary benefits extended to Pharmacy500 companies and associations (coming this spring!)
SureCost’s Inventory Management software supports smart inventory management, permitting you and your staff to complete tasks with increased speed and efficiency and freeing everyone up to handle customers’ needs. It offers robust perpetual and physical inventory management capabilities, along with formulary management tools, for:
Our software works with all major wholesalers—as well as with the vast majority of secondary providers, GPOs and other pharmaceutical sources. What’s more, SureCost can order the products your pharmacy needs, saving time and ensuring that items are received on schedule.
Manage inventory based on what’s physically on hand, taking customer orders, incoming/outgoing inventory transfers and purchase orders into consideration. Automatically generate accurate replenishment orders based on data and self-defined rules. Be informed about excessive inventory and identify instances where inventory was purchased, with no customer dispense orders received.
Manage inventory from wherever you want, whenever you like with the SureCost mobile app. Add items to open purchase order worksheets out on the floor or even from a remote location. Do quick cycle counts out on the floor without a laptop and cart. Easily request, receive and fill transfers.
Get real-time inventory valuation based on last acquired price. Identify stale or slow-moving products and initiate transfer of inventory to other departments or pharmacy locations—entirely automatically. Stay informed via transfer-tracking notifications.
Save more money with Inventory Management – Improved cash flow with a 10-20% reduction in inventory due to better forecasting of on hand quantities and elimination of excessive inventory
Unlike many other solutions of its type, SureCost DSCSA Compliance software simplifies and fully supports compliance with the Drug Supply Chain Security Act (DSCSA), increasing the convenience of managing DSCSA-relevant data and making it easy to maintain vendor accountability.
It provides just one interface and source of data for all trading partners, as required under all DSCSA. Easily tap into data and reports (including transaction information, transaction statement received and transaction history) that can help when fielding requests from or audits by manufacturers, the FDA and other authorities. Check the reconciliation page for lists of flagged products and reconciliation options.
Introducing DSCSA Compliance Packages from SureCost. Our packages will help with EPCIS data exchange with your vendors, capture data from traceable items in receiving, reconcile discrepancies, manage quarantined items, track traceable items across transfers and returns to your primary vendor, include six year data retention and deliver reporting around all of it.
The SureCost DSCSA Compliance Software streamlines inventory management while eliminating doubt and ensuring pharmacies are 100% DSCSA compliant.
SureCost helps pharmacies control spending and simplify purchasing by centralizing vendors, improving inventory visibility, and giving teams the tools to make smarter, more cost-effective decisions.
RxPost helps pharmacies reduce waste and strengthen their margins by giving them an easy, technician-informed platform to buy, sell, and redistribute inventory with confidence and real-world support.
McKesson is a complex company that touches many different aspects of pharmacy. This report gives a simplified overview of the company structure, products, mergers and acquisitions, and more. Read this report to learn more about how McKesson operates.
Automated Dispensing Cabinets (ADCs) are machines that store, manage, and dispense medications in hospital settings. They ensure medication security and help with inventory management. This report offers insight into Pharmacy500 companies that provide medication dispensing automation, including product comparisons, company insights, and more.
In this case study, we take a look at how Shingle Springs Health & Wellness Center utilizes Parata’s Beacon Inventory Management System and DeliverRx to streamline inventory management and efficiently manage will-call prescriptions.
In this case study, we take a look at how Cohen Children’s Medical Center utilized Swisslog Healthcare’s BoxPicker® Automated Pharmacy Storage System to streamline medication management, reduce picking errors, and improve efficiency and patient safety through centralized, automated inventory control.
In this case study, we take a look at how Guardian Pharmacy Services utilized SureCost’s Purchase Manager™ and Inventory Manager™ software to centralize procurement, optimize vendor compliance, and empower its national network of long-term care pharmacies to make smarter, data-driven purchasing decisions that improve efficiency and lower costs.
In this case study, we take a look at how HAC Pharmacies utilized SureCost’s unified purchasing and inventory management solution to centralize vendor data, drive smarter purchasing decisions, and save over $200,000 in just four months through data-driven cost optimization across 24 retail locations.
In this case study, we take a look at how Smith Pharmacy utilized SureCost’s integrated purchasing and inventory management platform to streamline vendor comparisons, improve pricing transparency, and save hundreds of thousands of dollars annually while enhancing patient affordability and operational efficiency
In this case study, we take a look at how Giant Eagle utilized Noritsu’s automated strip packaging technology to establish a scalable long-term care pharmacy operation, improving medication adherence, workflow efficiency, and patient care through advanced automation and system integration.
In this case study, we take a look at how EverSpring Pharmacy utilized Noritsu’s strip packaging automation technology to boost productivity, improve accuracy, and reduce labor costs while enhancing medication adherence and workflow efficiency in long-term care pharmacy operations.
In this case study, we examine Tension Packaging & Automation’s partnership with AFA Pharmacy to deploy the LDU-Flex system and PharmaPATH software, enabling the mail-order fulfillment center to efficiently scale daily orders with seamless automation and strong vendor support.
In this case study, we take a look at how CHRISTUS Health utilized AmerisourceBergen’s innovative RFID Pharmacy Technology to transform and streamline pharmacy inventory management across its enterprise.
The Cencora Company Teardown Report offers an in-depth analysis of one of the pharmacy industry’s most complex and influential organizations.
RXinsider’s Pharmacy500 Academy now offers training on medication inventory management and medication inventory software, along with product comparisons and company breakdowns. Visit the Pharmacy500 Academy to learn more about drug procurement.
September 2025 — Datarithm®, the trusted ally in pharmacy management, is announcing a powerful addition to its perpetual inventory management platform in the form of enhancements to its Liquidation Engine…
This case study details how Reasor’s Pharmacy achieved significant inventory management improvements within a year by implementing the Supplylogix Pinpoint product suite.
In this case study, we take a look at how Doylestown Health utilized Medi-Dose unit dose packaging technology to prevent the cross-contamination of hazardous drugs.
AdvanceNet Health Solutions Agadia
American Pharmacy
Cooperative, Inc. (APCI)
AnewHealth
ANiGENT LLC
ARxIUM
Asembia
AssistRx
AssureCare LLC
Avel eCare
Aventi Health
BD
BestRx
Bluesight
Capital Inventory, Inc
Cardinal Health
CarepathRx
CarePoint
Cencora/AmerisourceBergen
Codonics
ConsortiEX, Inc.
CORE Higher Education Group
CoverMyMeds (McKesson Corporation)
CPS Solutions, LLC
Crocus Medical Inc.
CuraScriptSD
Cypress Software, Inc.
Datarithm
Datascan Pharmacy, Inc.
Digital Business Solutions, Inc.
DocStation
DoseMe
DosePacker, Inc.
DosePlanner
DrFirst
DRX SOFTWARE LLC
EnlivenHealth
Epic Systems Corporation
Epicor Software Corporation
epocrates/Athenahealth
Euclid Medical Products
EzriRx
EZSCRIPTRx
FFF Enterprises, Inc.
First Databank, Inc.
Fullscript
GeriMed, Inc.
Health Care Logistics, Inc.
HelioMetrics
ICU Medical
Imprivata/FairWarning
InfiniTrak, LLC
InfoWerks
Inmar Inc.
Inovalon
InsightRX, Inc.
Institute for Safe Medication Practices (ISMP)
Intelliguard/MEPS
Real-Time, Inc.
Interlink AI, Inc.
International Medical Industries
Isak Computing (SiCompounding & SiPrescribe)
JFCRx
Keycentrix, LLC
Liberty Software
LifeFile
Loopback Analytics
Lumistry
MatchRX
McKesson Corporation
Medi-Dose, Inc./EPS, Inc.
Medicine-On-Time
Medigi
Meditech
MedMe Health
Merative
Micro Merchant Systems, Inc.
MIDAS Healthcare Solutions
Mobile MediClaim, Inc.
Noritsu Pharmacy Automation
Omnicell
OmniSYS (XiFin Pharmacy Solutions)
Optum, Inc.
Oracle Health/Cerner
OrderInsite, LLC
Outcomes
PDR/ConnectiveRx
PEPID, LLC
phactMI
Pharmacy Quality Solutions (PQS)
PharmaForce
Pharmapod
PharmaPoint, LLC
PharmID, Inc.
Plenful
PointClickCare
PPOk
PreciseRX
Premier
Prescryptive Health, Inc.
Protenus
Pyrls
QuicksortRx, Inc.
RedSail Technologies
Retail Management Solutions, LLC
RxConnexion
RxDispense
RxLive, Inc.
RxRise
RxScan
RxStrategies, Inc.
Sanford Guide
ScriptPro LLC
SoftWriters, Inc
Speed Script
SpendMend
Sphinx Strategies
SRS Pharmacy Systems
STACK, LLC
STChealth
SuiteRx, LLC
SureCost, LLC
Surescripts
Swisslog Healthcare
TailorMed
Terso Solutions, Inc.
The Craneware Group
ThoroughCare, Inc.
TraceLink, Inc.
TransferMyRx
Trilogy MedWaste, Inc.
TruMedSystems, Inc.
UGO
United States Pharmacopeia (USP)
VPL, Inc.
WeInfuse, LLC
Wolters Kluwer
Workflow Services
Yardi Systems, Inc.
Zebra Technologies Corp.