Pharmacy500 Marketplace

Medication Inventory Management & Procurement

Leading Providers of Pharmacy Inventory Software & Inventory Management...

Aisle OVERVIEW

Drug Procurement Software for pharmacies is a specialized software solution designed to streamline and automate the process of sourcing, comparing, purchasing, and managing the acquisition of medications and pharmaceutical supplies. It enables pharmacies to maintain optimal stock levels, compare wholesalers, negotiate with suppliers, and ensure compliance with regulatory and financial requirements.

Company Profiles

C2 Keep

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Join Over 2,000 Pharmacists and Staff Who Trust C2 Keep to Bring Peace of Mind 

C2 Keep is a cloud-based, fully integrated controlled substance reporting and compliance solution designed specifically for pharmacies. Founded by former pharmacy director Roland Achenjang after experiencing an embarrassing audit, C2 Keep was built to eliminate the same compliance challenges he and countless others have faced. 

By automating manual tasks, delivering real-time insights, enhancing security, and simplifying reporting, C2 Keep empowers pharmacies to stay compliant and focus on what matters most: ensuring patients receive the right medication at the right time. 

Why Pharmacies Choose C2 Keep 

  • Seamless Integration: C2 Keep is the only controlled substance compliance tool that integrates directly with your pharmacy management system and wholesalers. This provides a unified solution that removes data silos and improves operational efficiency. 
  • Transformative Time Savings: Replace cumbersome manual logbooks and save up to 25 hours per month or $15,000 annually in labor costs. This allows your team to focus more time on patient care and other high-value tasks that support your business. 
  • Real-Time Inventory Insights: C2 Keep’s true perpetual inventory tracking provides instant visibility into controlled substance activity. You and your team can easily maintain accurate records, make informed decisions, and strengthen operational performance. 
  • Enhanced Accountability & Security: Built-in safeguards increase staff accountability and make diversion more difficult. The system also enables quick identification and resolution of discrepancies, which helps create a safer environment for both staff and patients. 
  • Streamlined Compliance Reporting: Generate federal and state-mandated reports in seconds and prepare for DEA or board of pharmacy audits with confidence. C2 Keep simplifies compliance, saving time and reducing stress.
  • Effortless Document Management: Store and retrieve DEA 222 / CSOS documents and other order files in just a few clicks. C2 Keep keeps everything organized and secure, so your pharmacy is always audit-ready. 

Ready to Simplify Compliance? 

Whether you’re a small independent pharmacy or part of a larger chain, C2 Keep scales to meet your unique needs, providing a flexible compliance solution that grows with your business. Visit c2keep.com and schedule a demo to learn more!

Pharmacy500

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The Pharmacy500 is awarded to 500 pharmacy supply chain businesses and associations that significantly impacted dispensing pharmacies in the U.S. over the past year.

Pharmacy500 Benefits

The following are complimentary benefits extended to Pharmacy500 companies and associations (coming this spring!)

  1. Company listings in the Platinum Pages Buyer’s Guide, 20Ways publications, and RXinsider website
  2. Company inclusion in the 20Ways themed Buyer’s Guide
  3. Unlimited job postings in the Pharmacy500 Career Center *Unlimited through 2025
  4. Tradeshow promotional resources including Pharmacy500 floor stickers and lanyards
  5. Two posts (annually) in RXinsider’s Pharmacy Market BUZZ news feed

Who are the Pharmacy500 and what are the selection criteria?

The Pharmacy500 includes:

  1. Companies within the Pharmacy Supply Chain
  2. National Pharmacy Trade Associations

The Pharmacy500 Selection Committee applies the following criteria to determine the list of 500:

  • Offers and actively markets at least one product or service to dispensing pharmacies
  • Dispensing pharmacies comprise at least 25% of their customer base
  • Has an estimated annual revenue exceeding $500,000
  • Has five or more full-time employees, and has been in business for more than two years
  • Has a national presence
  • Exhibited at one of the following national conferences in the previous year: APhA; ASCP Annual Meeting & Exhibition; Asembia’s Summit; ASHP Midyear Clinical Meetings & Exhibition; Cardinal Health RBC; McKesson ideaShare; NACDS Total Store Expo; NASP Annual Meeting & Expo; NCPA Annual Convention and Expo; Pharmacy Futures (ASHP Summer); ThoughtSpot.

The following supply chain segments are critical to pharmacy operations and patient care, but are excluded from the Pharmacy500 simply due to volume:

  • Manufacturers and Merchandisers of Pharmaceuticals
  • Manufacturers and Merchandisers of Devices and OTC Products
  • Colleges of Pharmacy
  • State Associations
  • Government Agencies and State Boards of Pharmacy
  • Pharmacy Fraternities & Sororities
  • Dispensing Pharmacies, Health Systems, Chains, Payors, and PBMs

SureCost

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The Problem Pharmacies Face

Too many systems. Not enough clarity.

Pharmacies are navigating rising costs, supply disruptions and increasing compliance demands while relying on fragmented data and manual processes.

When purchasing visibility is limited, teams are forced into reactive decisions that increase margin leakage and operational inconsistency.

The SureCost Difference

One source of truth for pharmacy procurement.

SureCost is a pharmacy procurement platform that centralizes purchasing data, pricing validation and compliance visibility into a single system.

It works alongside existing pharmacy systems, vendors and GPO relationships to provide independent oversight without disrupting workflows.

What SureCost Delivers

Clear decisions backed by verified data.

With SureCost, pharmacy teams can:

  • See purchasing activity across vendors and accounts in one place
  • Validate pricing and contract adherence at the time of purchase
  • Identify discrepancies before they impact margins
  • Reduce variance caused by fragmented workflows
  • Strengthen vendor accountability through clearer performance insight
  • Access centralized documentation that supports audit readiness

Purchasing Visibility Without the Guesswork

Know what you are buying and why it matters.

SureCost connects  pricing, contract alignment and purchasing patterns so teams can see where decisions deviate, why it happens and what it costs the organization

This visibility helps pharmacy leaders move from reactive purchasing to proactive procurement management.

Compliance Without Added Complexity

Audit-ready documentation without manual work.

Managing compliance across multiple systems creates risk and unnecessary burden. SureCost simplifies this by centralizing reporting, verification and documentation into one platform.

Pharmacies gain:

  • Standardized compliance reporting
  • Audit-ready records in one location
  • Reduced reliance on after-the-fact reconciliation
  • Greater confidence in contract alignment

Built to Fit How Pharmacies Operate

Oversight without replacement.

SureCost doesn’t replace existing pharmacy platforms. It layers independent oversight on top of current processes so teams gain control and visibility without retraining staff or changing vendor relationships

Proven Across Pharmacy Environments

Trusted by more than 1,600 pharmacies.

Pharmacy organizations using SureCost consistently report:

  • Meaningful time savings for purchasing teams
  • Improved visibility across vendors and accounts
  • Stronger margin control through verified purchasing decisions

Centralized oversight helps pharmacies reduce risk, improve consistency and operate with greater confidence.

Why It Matters

Less uncertainty. More control.

SureCost replaces fragmented views with a single source of truth for pharmacy procurement so pharmacy teams can focus less on chasing data and more on informed decision-making.

Simplifying Procurement So Teams Can Focus on What Matters

Clear insight. Confident decisions.

SureCost helps pharmacy leaders bring clarity to procurement strategy, day-to-day purchasing and long-term planning so teams can focus on patient care, operational excellence and sustainable growth.

AdvanceNet Health Solutions

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At AdvanceNet Health Solutions (ANSHealth), we’re dedicated to being the world’s premier ePharmacy technology company. Our ePostRx product enables pharmacies to facilitate higher fulfillment volumes, enhance patient care and increase profitably by supporting multiple business models, including Electronic Scripts, Retail, Chain Retail, Mail-Order and Central Fill. Now ePostRx is the healthcare industry’s first and only open source, enterprise pharmacy solution licensed under GNU General Public License (GPL). So if your business requires:

  • Prescription Fulfillment/Management Software
  • ePrescribing Translation/Management Software
  • Pharmacy Operations & Technology Consulting
  • Open source technology consulting and Project Development.

Then contact ANSHealth and get involved with the ePostRx community today!

Product Highlight SHOWCASE

Subject Matter Expert & Thought Leader PROFILES

Resources & Awareness

SureCost helps pharmacies control spending and simplify purchasing by centralizing vendors, improving inventory visibility, and giving teams the tools to make smarter, more cost-effective decisions.

RxPost helps pharmacies reduce waste and strengthen their margins by giving them an easy, technician-informed platform to buy, sell, and redistribute inventory with confidence and real-world support.

McKesson is a complex company that touches many different aspects of pharmacy. This report gives a simplified overview of the company structure, products, mergers and acquisitions, and more. Read this report to learn more about how McKesson operates.

Automated Dispensing Cabinets (ADCs) are machines that store, manage, and dispense medications in hospital settings. They ensure medication security and help with inventory management. This report offers insight into Pharmacy500 companies that provide medication dispensing automation, including product comparisons, company insights, and more.

In this case study, we take a look at how Shingle Springs Health & Wellness Center utilizes Parata’s Beacon Inventory Management System and DeliverRx to streamline inventory management and efficiently manage will-call prescriptions.

In this case study, we take a look at how Cohen Children’s Medical Center utilized Swisslog Healthcare’s BoxPicker® Automated Pharmacy Storage System to streamline medication management, reduce picking errors, and improve efficiency and patient safety through centralized, automated inventory control.

In this case study, we take a look at how Guardian Pharmacy Services utilized SureCost’s Purchase Manager™ and Inventory Manager™ software to centralize procurement, optimize vendor compliance, and empower its national network of long-term care pharmacies to make smarter, data-driven purchasing decisions that improve efficiency and lower costs.

In this case study, we take a look at how HAC Pharmacies utilized SureCost’s unified purchasing and inventory management solution to centralize vendor data, drive smarter purchasing decisions, and save over $200,000 in just four months through data-driven cost optimization across 24 retail locations.

In this case study, we take a look at how Smith Pharmacy utilized SureCost’s integrated purchasing and inventory management platform to streamline vendor comparisons, improve pricing transparency, and save hundreds of thousands of dollars annually while enhancing patient affordability and operational efficiency

In this case study, we take a look at how Giant Eagle utilized Noritsu’s automated strip packaging technology to establish a scalable long-term care pharmacy operation, improving medication adherence, workflow efficiency, and patient care through advanced automation and system integration.

In this case study, we take a look at how EverSpring Pharmacy utilized Noritsu’s strip packaging automation technology to boost productivity, improve accuracy, and reduce labor costs while enhancing medication adherence and workflow efficiency in long-term care pharmacy operations.

In this case study, we examine Tension Packaging & Automation’s partnership with AFA Pharmacy to deploy the LDU-Flex system and PharmaPATH software, enabling the mail-order fulfillment center to efficiently scale daily orders with seamless automation and strong vendor support.

In this case study, we take a look at how CHRISTUS Health utilized AmerisourceBergen’s innovative RFID Pharmacy Technology to transform and streamline pharmacy inventory management across its enterprise.

The Cencora Company Teardown Report offers an in-depth analysis of one of the pharmacy industry’s most complex and influential organizations.

RXinsider’s Pharmacy500 Academy now offers training on medication inventory management and medication inventory software, along with product comparisons and company breakdowns. Visit the Pharmacy500 Academy to learn more about drug procurement.

September 2025 — Datarithm®, the trusted ally in pharmacy management, is announcing a powerful addition to its perpetual inventory management platform in the form of enhancements to its Liquidation Engine…

This case study details how Reasor’s Pharmacy achieved significant inventory management improvements within a year by implementing the Supplylogix Pinpoint product suite.

In this case study, we take a look at how Doylestown Health utilized Medi-Dose unit dose packaging technology to prevent the cross-contamination of hazardous drugs.

Pharmacy500

AdvanceNet Health Solutions Agadia
American Pharmacy
Cooperative, Inc. (APCI)
AnewHealth
ANiGENT LLC
ARxIUM
Asembia
AssistRx
AssureCare LLC
Avel eCare
Aventi Health
BD
BestRx
Bluesight
Capital Inventory, Inc
Cardinal Health
CarepathRx
CarePoint
Cencora/AmerisourceBergen
Codonics
ConsortiEX, Inc.
CORE Higher Education Group
CoverMyMeds (McKesson Corporation)
CPS Solutions, LLC
Crocus Medical Inc.
CuraScriptSD
Cypress Software, Inc.
Datarithm
Datascan Pharmacy, Inc.
Digital Business Solutions, Inc.
DocStation
DoseMe
DosePacker, Inc.
DosePlanner
DrFirst
DRX SOFTWARE LLC
EnlivenHealth
Epic Systems Corporation
Epicor Software Corporation
epocrates/Athenahealth
Euclid Medical Products
EzriRx
EZSCRIPTRx
FFF Enterprises, Inc.
First Databank, Inc.
Fullscript
GeriMed, Inc.
Health Care Logistics, Inc.
HelioMetrics
ICU Medical
Imprivata/FairWarning
InfiniTrak, LLC
InfoWerks
Inmar Inc.
Inovalon
InsightRX, Inc.
Institute for Safe Medication Practices (ISMP)
Intelliguard/MEPS
Real-Time, Inc.
Interlink AI, Inc.
International Medical Industries
Isak Computing (SiCompounding & SiPrescribe)
JFCRx
Keycentrix, LLC
Liberty Software
LifeFile
Loopback Analytics
Lumistry
MatchRX
McKesson Corporation
Medi-Dose, Inc./EPS, Inc.
Medicine-On-Time
Medigi
Meditech
MedMe Health
Merative
Micro Merchant Systems, Inc.
MIDAS Healthcare Solutions
Mobile MediClaim, Inc.
Noritsu Pharmacy Automation
Omnicell
OmniSYS (XiFin Pharmacy Solutions)
Optum, Inc.
Oracle Health/Cerner
OrderInsite, LLC
Outcomes
PDR/ConnectiveRx
PEPID, LLC
phactMI
Pharmacy Quality Solutions (PQS)
PharmaForce
Pharmapod
PharmaPoint, LLC
PharmID, Inc.
Plenful
PointClickCare
PPOk
PreciseRX
Premier
Prescryptive Health, Inc.
Protenus
Pyrls
QuicksortRx, Inc.
RedSail Technologies
Retail Management Solutions, LLC
RxConnexion
RxDispense
RxLive, Inc.
RxRise
RxScan
RxStrategies, Inc.
Sanford Guide
ScriptPro LLC
SoftWriters, Inc
Speed Script
SpendMend
Sphinx Strategies
SRS Pharmacy Systems
STACK, LLC
STChealth
SuiteRx, LLC
SureCost, LLC
Surescripts
Swisslog Healthcare
TailorMed
Terso Solutions, Inc.
The Craneware Group
ThoroughCare, Inc.
TraceLink, Inc.
TransferMyRx
Trilogy MedWaste, Inc.
TruMedSystems, Inc.
UGO
United States Pharmacopeia (USP)
VPL, Inc.
WeInfuse, LLC
Wolters Kluwer
Workflow Services
Yardi Systems, Inc.
Zebra Technologies Corp.

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